Medicine

Novartis aims to broaden use of breast cancer drug

Novartis aims to broaden use of breast cancer drug

MONALEESA-7 is the first prospective global phase III trial in more than 20 years, designed specifically for premenopausal women diagnosed with advanced breast cancer, to demonstrate superiority of any CDK4/6 inhibitor in combination with oral hormonal therapies and goserelin versus endocrine treatment alone in this patient population.

Women who choose to be apart of the WISDOM study have to be a Sanford patient, between the ages of 40 to 74, with no history of breast cancer.

"The results of the PANACEA study are very encouraging", stated Dr Sherene Loi, PhD, associate professor at Peter MacCallum Cancer Centre in Melbourne, Australia, who works with the International Breast Cancer Study Group (IBCSG). The improvement in mean BPI "worst pain" score for those receiving true acupuncture remained significant compared to the other two group's scores over 24 weeks.

The new study was led by Dr. Dawn Hershman, who heads the Breast Cancer Program at NewYork-Presbyterian/Columbia University Medical Center, also in New York City.

Results from the PANACEA study, recently presented at the San Antonio Breast Cancer Symposium, have suggested that immunotherapy may help to overcome trastuzumab-resistant breast cancer. The most common adverse event reported among those receiving true and sham acupuncture was bruising.

More news: China coal imports rise in November despite push against pollution

"Our goal was to provide an alternative to pain medications to control this side effect", said Dr. Hershman.

"Longer follow-up is needed to determine whether the trial will meet its secondary end point of overall survival", Tripathy said in a statement.

In the meantime, the findings suggest that "health care practitioners should discuss the possibility of acupuncture with patients experiencing aromatase inhibitor-related joint pain and stiffness, because it has the potential to improve their quality of life", Hershman said.

"This is yet another study that reveals the benefits of acupuncture in treating pain", Coomer said.

According to Dr. Hershman and Dr. Crew, many patients don't want to take additional medications to relieve symptoms caused by aromatase inhibitors.


  • Most Americans say senior Trump officials probably had 'improper' contact with Russian Federation

    Most Americans say senior Trump officials probably had 'improper' contact with Russian Federation

    About a quarter of conservatives said that the officials likely had improper contacts, while more than 80 percent of liberals did. Democrats and Republicans were starkly divided in their beliefs on the issue.
    Five frontier states in east to get border security grid: Rajnath Singh

    Five frontier states in east to get border security grid: Rajnath Singh

    According to an official estimate of India, around 36,000 Rohingyas are now living in various parts of India. He said that out of 4096 km Indo-Bangla border, installation of fencing has so far done in 3006 km.
    US House ethics panel probing Rep. Blake Farenthold over harassment allegations

    US House ethics panel probing Rep. Blake Farenthold over harassment allegations

    However, it noted that "establishing an investigative subcommittee does not itself indicate that any violation has occurred". While the committee's statement did not name her, a lawyer for Farenthold's former staffer confirmed her identity last week.
  • Manila to sue Sanofi over dengue vaccine

    Manila to sue Sanofi over dengue vaccine

    The symptoms of severe dengue include fever lasting for at least two days, low platelet count, bruising and severe bleeding. In addition, DOH will demand Sanofi to cover the hospitalization of those who will contract severe dengue from the vaccine.

    Conagra Brands, Inc. (CAG) EPS Estimated At $0.52

    Market capitalization is calculated by multiplying a company's shares outstanding by the current market price of one share. What Historical Figures Say About Conagra Brands, Inc . (NYSE: CAG ). 660,117 were reported by Voloridge Invest Mgmt.
    Rep. Gowdy: Why Was Anti-Trump FBI Agent Interviewing Hillary?

    Rep. Gowdy: Why Was Anti-Trump FBI Agent Interviewing Hillary?

    The former counterintelligence agent also interviewed Michael Flynn in January about the Russian Federation investigation . Strzok sent negative text messages about Trump during the 2016 presidential election.
  • Virat and Anushka leave for Europe with Sharma family priest. Wedding confirmed?

    Virat and Anushka leave for Europe with Sharma family priest. Wedding confirmed?

    A spokesperson for Anushka told news agency PTI soon after that "there is absolutely no truth to it (rumours of marriage)". As netizens were going gaga over pictures of their gardening date , their families met and discussed their wedding dates.
    Indonesia's FM Summons US Ambassador On President Trump's Statement

    Indonesia's FM Summons US Ambassador On President Trump's Statement

    A statement posted on the Indian Foreign Ministry website said: "India's position on Palestine is independent and consistent". With parliamentary elections scheduled for next year, Malaysia's Prime Minister Najib Razak was more forceful.

    Candriam Luxembourg SCA Cuts Holdings in CarMax Inc (KMX)

    CarMax Inc . has had 26 insider trades in the last 3 months, including 0 open market buys and 26 sells. On Tuesday, December 15 the stock rating was maintained by RBC Capital Markets with "Sector Perform".
  • Cold rain, some wintry weather possible Friday

    Cold rain, some wintry weather possible Friday

    Most of the models show most (if any) accumulation staying north of us in parts of Metro Atlanta and along I-85 in North Georgia. Watch for last-minute forecast changes; if you are using a forecast more than six hours old, it is bad information.

    Schlumberger Limited. (SLB) Position Boosted by Intact Investment Management Inc

    GEODE CAPITAL MANAGEMENT, LLC also announced increased position in TransEnterix, Inc. (NASDAQ:MELI) rating on Wednesday, July 19. Moreover, Wg Shaheen And Associates Dba Whitney And has 0.51% invested in Schlumberger Limited (NYSE:SLB) for 23,640 shares.
    Stryker to buy Entellus Medical for $662 mln (SYK)

    Stryker to buy Entellus Medical for $662 mln (SYK)

    The P/E ratio is one of the most common ratios used for figuring out whether a company is overvalued or undervalued. ValuEngine raised Entellus Medical from a "strong sell" rating to a " sell" rating in a research note on Friday.