Medicine

Aspirin doesn't lower heart attack and stroke risks and can increase bleeding

Aspirin doesn't lower heart attack and stroke risks and can increase bleeding

The student was led by researched at Monash University and was publishes in the New England Journal of Medicine.

After about five years of treatment, the rate of heart disease was not significantly lower in the 9,525 volunteers taking 100mg of aspirin daily than in the 9,589 who took placebo tablets.

The study found a daily low dose of aspirin did not reduce risks of certain diseases and medical problems in older people.

The participants were then followed for an average of 4.7 years.

He warned that the results do not apply to people with existing conditions such as a previous heart attack, angina or stroke, where aspirin is recommended to prevent further illness.

One surprise for the researchers was that the group that took aspirin died at a slightly higher rate from all causes than the group that did not take it.

Major risks of bleeding in people who consume aspirin on a daily basis overwhelm its benefits. You should rather ask your doctor for guidance on which steps you will need to take going forward. Half of those people used daily aspirin and the others did not.

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Scientists at Monash University in Australia enrolled 19,114 people aged 65 and older in Australia and the U.S., randomly giving them a daily low-dose aspirin or a placebo. In the final 12 months of the trial, 62.1 percent of the participants in the aspirin group and 64.1 percent of those in the placebo group reported that they were still taking their assigned dosage.

Instead, it focused on answering the question of whether the drug reduced the risk of healthy seniors suffering their first heart attack or stroke, or losing their good health.

In the meantime, experts are warning against healthy people simply popping an aspirin every day and believing it will fix everything that ails them.

Doctor Evan Hadley, of the NIA, added: 'Continuing follow-up of the ASPREE participants is crucial, particularly since longer term effects on risks for outcomes such as cancer and dementia may differ from those during the study to date.

"The authors rightly suggest treating the unexpected effects with caution, but they also show that benefits of aspirin in healthy people are at best limited, and may well be harmful, and this harm may be increased beyond age 73". Patients who were black or Hispanic and living in the USA were included in the study as they face a higher risk of heart disease or dementia generally.

Clinically significant bleeding - hemorrhagic stroke, bleeding in the brain, gastrointestinal hemorrhages or other hemorrhages that required transfusion or hospitalisation - occurred in 3.8 per cent on aspirin and in 2.7 per cent taking the placebo. Numerous extra deaths were due to cancer, but Leslie Ford from the National Cancer Institute in Maryland said that until the team had analysed more data, the cancer findings "should be interpreted with caution".

For cardiovascular disease, the rate was 10.7 events per 1000 person-years in the aspirin group and 11.3 events per 1000 person-years in the placebo group - also considered no difference.


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