Medicine

The presence of the Appendix blocks the development of Parkinson’s disease

The presence of the Appendix blocks the development of Parkinson’s disease

Getting the appendix removed early in life significantly reduces a person's risk of developing Parkinson's Disease, a study has found.

In Parkinson's disease, toxic proteins accumulate in the brain and kill nerves, especially those linked to movement.

Although they do not advise that people go and have their appendix removed, as this is not a sure protection against Parkinson's disease. However, Labrie warned that appendectomy does not guarantee that a person will not be diagnosed with Parkinson's.

The reasoning is due to surgically removed appendix tissue becoming a storage space for abnormal protein that, if it makes its way to the brain, becomes the trademark of the tremor-inducing brain disease.

Scientists have found further evidence that the gut, or more specifically the appendix, might play a role in the development of Parkinson's disease. NutraIngredients reported previously on the theory that gut microbes may trigger Parkinson's disease.

Could the appendix be the cause of Parkinson's?

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The contents of people's appendix have been examined and it has been discovered that it has the toxic protein called alpha synuclein - that is found in the brains of Parkinson's patients.

There are plenty of people that still develop Parkinson's with no appendix and others that don't get sick despite carrying the protein.

University of Pennsylvania neuroscience and geriatric medicine professor John Trojanowski, who was not involved in the study, thought it was excellently done and agreed with the paper's statement that the appendix is a source of mis-folded alpha-synuclein that could be targeted for therapeutic strategies.

The researchers, led by assistant professor Vivian illustrious Research Institute Van 'Adel Michigan who analyzed data for about 1.7 million.

Viviane Labrie, an assistant professor at Van Andel Research Institute in MI and senior author of the study, said: "Despite having a reputation as largely unnecessary, the appendix actually plays a major part in our immune systems, in regulating the makeup of our gut bacteria and now, as shown by our work, in Parkinson's disease".


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